The CTIF is supported through institutional and programmatic grants, as well as through collaborative investigator grants or subcontracts on CTIF user grants. Occasionally, infrequent microscopy users are billed at a calculated hour rate for technical expertise and equipment time. This structure allows new CTIF users to generate preliminary data in preparation for future grant submissions. In general, occasional chargeback users are not trained in the methods or instruments within the facility. Therefore, most of their studies have to be performed by facility staff to optimize results and to avoid damage to instrumentation.