UPMC Hillman Cancer Center

Shandong Wu, PhD

Shandong Wu
Assistant Professor of Radiology, Biomedical Informatics, and Bioengineering

Contact Information

Contact Information

200 Lothrop St.
Pittsburgh, PA 15213

Email: wus3@upmc.edu

Research Keywords

Research Keywords

Breast imaging; breast cancer screening; early diagnosis; computational biology; MRI-based biomarkers; breast cancer risk; personalized medicine

Research Summary

Research Summary

I am a computational scientist with training in radiology. My research interests include a broad range of quantitative breast imaging analyses for translational and clinical applications. In particular, I am investigating the role of imaging as a biomarker for improving personalized breast cancer screening, diagnosis, prognosis, and treatment. My current research focuses on: 1) development of computational tools for automated and quantitative breast image analysis; and 2) breast MRI-based biomarkers for breast cancer risk assessment and risk-reducing interventions in women at high risk for the disease.

Selected Publications

Selected Publications

  • Schmitz KH, Williams NI, Kontos D, Domchek S, Morales KH, Hwang WT, Grant LL, DiGiovanni L, Salvatore D, Fenderson D, Schnall M, Galantino ML, Stopfer J, Kurzer MS, Wu S, Adelman J, Brown JC, Good J. Dose-response effects of aerobic exercise on estrogen among women at high risk for breast cancer: a randomized controlled trial. Breast Cancer Res Treat. 2015 Nov;154(2):309-18. PubMed Link
  • Wu S, Weinstein SP, DeLeo MJ 3rd, Conant EF, Chen J, Domchek SM, Kontos D. Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers. Breast Cancer Res. 2015 May 19;17:67. PubMed Link
  • Schmitz KH, Williams NI, Kontos D, Kurzer MS, Schnall M, Domchek S, Stopfer J, Galantino ML, Hwang WT, Morales K, Wu S, DiGiovanni L, Salvatore D, Fenderson D, Good J, Sturgeon K, Grant L, Bryan CJ, Adelman J. Women In Steady Exercise Research (WISER) Sister: study design and methods. Contemp Clin Trials. 2015 Mar;41:17-30. PubMed Link
  • Wu S, Weinstein SP, Conant EF, Kontos D. Automated fibroglandular tissue segmentation and volumetric density estimation in breast MRI using an atlas-aided fuzzy C-means method. Med Phys. 2013 Dec;40(12):122302. PubMed Link
  • Wu S, Weinstein SP, Conant EF, Schnall MD, Kontos D. Automated chest wall line detection for whole-breast segmentation in sagittal breast MR images. Med Phys. 2013 Apr;40(4):042301. PubMed Link
  • Wu S, Weinstein S, Kontos D. Atlas-based probabilistic fibroglandular tissue segmentation in breast MRI. Med Image Comput Comput Assist Interv. 2012;15(Pt 2):437-45. PubMed Link

See all pubs (Pubmed)

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Last modified: 7/21/16